Research + Innovation

National NIOSH symposium here July 12-13

A national safety symposium taking place at the University of Cincinnati this week looks at successful partnership models from around the country, and broadcasts some of its sessions live.Read the full story here.

Latest in Research + Innovation
Foxfire helps firefighters with smoke vision

Former Eli Lilly sales manager and volunteer firefighter Zachary Green started MN8 Products, which makes Foxfire high intensity photo luminescent (glow in the dark) coatings and products for firefighters, in 2010. Green, a Marine Corps veteran, worked in the corporate world for 18 years, first for SAP and then later for Eli Lilly. He had been at Lilly for eight years when the economic recession hit. His choice: move to Indianapolis or take a corporate buyout during one of the worst recessions in history. "I'm not the type of guy that's meant to be in a cube," says Green.  As a volunteer firefighter, Green saw an opportunity to use the glow technology to coat equipment that firefighters use in the dark. "I had put the coating on my helmet and then used it in a fire," he says. "The other firefighters were amazed at how effective it was and wanted to use it on their helmets. I knew we were on to something." Three of the top risks faced by firefighters are visibility, accountability and disorientation. Foxfire illumination helps firefighters keep track of their tools and each other in a dark, smoky fire. The turning point for Green was the Fire Department Instructors Conference (FDIC) in Indianapolis, the largest conference and tradeshow for firefighters, which welcomes 34,000 firefighters every year. "We were the busiest booth in the tradeshow," Green says. "We ran out of product samples three times and had to send people back to Cincinnati to get more." That month, the company received over $85,000 in orders, beginning a trend that hasn't stopped. The new challenge is managing a startup that is growing really quickly – and keeping enough cash in hand to turn around orders. Green has self-financed his company and has used a line of credit to manage the time between manufacturing product and getting payments from customers. "My training from the Marine Corps taught me to always plan for the worst case scenario, so I had contingency plans for how to manage large, unexpected orders," Green says. Despite the anxiety that comes with starting a new company in a down economy, Green has no regrets. "I'm having the time of my life."By Elizabeth Edwards

Radio captioning technology debuts in Ft. Mitchell

The company that first captioned radio so that people who are deaf or hard-of-hearing don't miss out on the latest news is demonstrating yet another piece of translational technology this week in Northern Kentucky.NPR Labs, the research and development arm of National Public Radio, has been working on ways to caption radio broadcasts for years. Products include on-screen captions as well as a dual-screen option for cars that allows drivers to see only a customized map of their location while passengers view a printed story on the same screen from a different angle.So when visually impaired listeners spoke out, anxious to receive the same kind of access to written news as their peers, NPR Labs responded. The new technology uses some elements of existing translation devices to create a direct port from the written transcript to transfer it to Braille. NPR Labs chose to debut and test their innovative new product at the American Association of the Deaf-Blind (AADB) 2011 National Symposium, a gathering of service support providers as well as the deaf-blind. It runs June 19 through 24 in Ft. Mitchell.Do Good:• Check out the agenda for the symposium.• Learn more about accessible radio.• Give a gift to support the work of Support Service Providers for the deaf-blind.By Elissa YanceyPhoto courtesy NPR Labs

Airway Therapeutics helps premature infants with healthy lung development

 In 2008, more than 530,000 babies were born prematurely in the U.S. That's about one in eight babies, according to the March of Dimes. Many have lungs that are not yet fully developed. That's where Airway Therapeutics comes in - the local business was created to help premature infants with their lung development and even survival rates.Based on 10 years of research at Cincinnati Children's Hospital Medical Center, Airway Therapeutics was created to develop a surfactant protein that lines the surface and airways of babies' lungs to help inflate them and keep their air sacs from collapsing. Airway's initial focus will be on the prevention of bronchopulmonary dysplasia (BPD) and also the prevention and treatment of neonatal respiratory distress syndrome (nRDS) in very premature infants. Normally, lungs mature to produce surfactant in the seventh month of gestation. Very premature infants (before 32 weeks gestation) have generally not developed lung surfactant to make the transition during birth from fluid-filled lungs to lungs that can easily expand to handle air movement. Administering surfactant to these very premature infants shortly after birth allows them to breathe. Airway's product, rhSP-D, would be added to existing surfactant prior to treating a premature newborn, and has been shown in the lab of Dr. Jeffrey Whitsett to be useful in reducing lung inflammation, a condition associated with BPD. Dr. Whitsett is chief of the Section of Neonatology, and Perinatal and Pulmonary Biology at Children's. Bringing his research into the market is CEO Steve Linberg, Ph.D., who has more than 30 years of clinical research, drug development and biologic development experience. The company recently received a seed-stage investment by CincyTech - a Cincinnati-based venture development firm that invests in technology-based startup companies - and the Cincinnati Children's Tomorrow Fund. Each has invested $250,000 as part of a projected $1.2 million seed-stage funding round led by CincyTech. The company is headquartered at BioStart, the Cincinnati bioscience startup center located in Clifton, which is a previous investor in Airway.The new investment will allow Airway to meet with the Food and Drug Administration within a few months to confirm their plans to begin developing rhSP-D in combination with an already-available surfactant, and then file an Investigational New Drug (IND) application within 15 months. Linberg estimates a total estimated cost of $25 million to bring the drug to market."This drug will save babies that don't survive today and radically improve the lives of millions of others," says CincyTech Executive-in-Residence Mike Venerable.Writer: Sarah Blazak

Northern Kentucky ezone taking applications for varied funding opportunities

Northern Kentucky tech, science and medical entrepreneurs have a chance to tap one of three state funds for seed capital through the end of this month. The Kentucky Enterprise Fund, Rural Innovation Fund and Kentucky New Energy Ventures Fund are accepting applications for funding through June 23 at 4 p.m. These three targeted funds are geared toward high-growth potential businesses in five sectors: Biosciences, Environmental & Energy Technologies, Human Health & Development, Information Technology & Communication and Materials Science & Advanced Manufacturing. In the last round of funding more than $600,000 was awarded statewide to companies. Past recipients in Northern Kentucky include Jacobs Automation, Zoomessence, Bexion Pharma, ASAP Analytical, and TodayForward.Northern Kentucky businesses can submit applications through Northern Kentucky ezone, a division of Northern Kentucky Tri-ED that has a mission of accelerating start-up, emerging and existing high-tech businesses."This is open to early stage companies from an idea to a company that is running and looking to grow," said ezone commercialization director T. Keith Schneider.Companies can apply for a combination of direct funding (that must be repaid) or matching grants. To find out more or to apply, contact Schneider at (859) 292-7785 or tks@northernkentuckyusa.com.  Following are the basics on each fund: Kentucky Enterprise Fund Eligible Companies: Must be Kentucky-based and have 150 or fewer employees. Must be operating in one of the following industries: Biosciences, Environmental & Energy Technologies, Human Health & Development, Information Technology & Communication or Materials Science & Advanced Manufacturing. Funding: Grant: $30,000. Company must match the grant 1:1 through cash or in-kind services.Funds must be used for approved business development activities. Investment: Up to $250,000, $500,000, and $750,000, must be repaid. Rural Innovation Fund Eligible Companies: Must be Small, Rural (located outside Fayette/Jefferson Counties), Kentucky-based company and have 50 or fewer employees. Must be operating in one of the following industries: Biosciences, Environmental & Energy Technologies, Human Health & Development, Information Technology & Communication or Materials Science & Advanced Manufacturing Funding: Grant: $30,000. Rural funds must be spent with independent third-party partners/consultants. Grants must be repaid upon receipt of follow-on award from Rural Innovation Fund or Kentucky Enterprise Fund. Funds must be used for approved business development activities. Investment: $100,000 must be repaid Kentucky New Energy Ventures Eligible Companies: KNEV will provide support for companies developing and commercializing products in the following areas: Alternative transportation fuels produced from coal, waste coal, biomass or extract oil from oil shale, synthetic natural gas, Ethanol produced from food crops or cellulosic ethanol, any other fuel that is produced from a renewable or sustainable source. Must be Kentucky-based and have 150 or fewer employees. Must be developing/commercializing alternative fuel and renewable energy products, processes, and services. Funding: Grant: $30,000. Company must match the grant 1:1 through cash or in-kind services. Funds must be used for approved business development activities.Investment: Any amount over $30,000. Companies must match the fund's investment on a 1:1 dollar ratio. Funds may be invested via convertible note or through direct stock.Investments can only be made in a company organized as a C Corp. or as an LLC Writer: Feoshia HendersonSources: ezone commercialization director T. Keith Schneider and Start-Up Kentucky You can follow Feoshia on Twitter @feoshiawrites

Energy assessments offer layers of savings for homeowners

For a limited time, homeowners in Hamilton, Boone, Campbell and Kenton counties can spend just $50 for a $400 to $500 review of potential energy inefficiencies in their homes, and then apply that $50 toward improvements that will help lower their energy bills.An initiative of the non-profit Greater Cincinnati Energy Alliance, the discounted three to five-hour energy assessment includes an in-depth examination of how well your home's heating and air conditioning are working, as well as trouble-shooting for potential leaks and gaps in insulation. "It doesn't matter if a home is five years old or 105 years old, there are cost effective energy upgrades in almost every home we've ever looked at," says Andy Holzhauser, GCEA's executive director. "It's our job to make the process easy and affordable for everyone in our community."Holzhauser believes connecting homeowners with local contractors who have been trained to find affordable, environmentally sustainable ways to retrofit homes creates a powerful motivation for living green. So, after the energy assessment, the GCEA will discount up to 35 percent of the cost of projects that assessors recommend. "We make the retrofit more affordable," Holzhauser says. "In the case of a $5,000 retrofit, we will put $1,700 to $1,800 of our dollars on the table right alongside the homeowner's investment."Best of all, there are no income restrictions on the discounted assessments and retrofit projects, both of which can lead to lower monthly living costs and better environmental stewardship. "The notion of an investment on a home actually generating a cash return back to you is something that is new," Holzhauser says. "It's at the heart of what we do."Do Good:• Watch a home energy assessment in action.• Find out how much you could save. Sign up to learn your potential savings and request an audit of your own.• Tweet and learn. Follow GCEA on Twitter.By Elissa Yancey Photo by Scott Beseler

New research could shift cities to emulate

We have issues. Specifically, health, social and economic issues in Greater Cincinnati that local researchers explore and write about on the Community Research Collaborative Blog.Monthly entries feature content from researchers at the United Way of Greater Cincinnati and the University of Cincinnati http://uc.edu . On the blog, three 2011 Community Research Collaborative fellows, along with other community contributors, work to describe the socio-economic health of our community.Each month a new post offers a new analysis. The May 2011 post, for example, compares the 1999 and 2009 data about Cincinnati's income growth, which is a measure of all sources of personal income, including wages, health insurance and a wide range of other benefits. The results showed significant progress as well as sobering realities. While the metropolitan area moved from 58th to 24th place out of 366 areas around the country, Cincinnati, along with many of its regional peers, grew slower than the national average. But Cincinnati wasn't alone. Nearly all of the regional competitors that the CRC uses to track our region's progress posted slowed growth. Those cities include: Austin, TX, Louisville, Charlotte, NC, Cleveland, Columbus, Denver, Indianapolis, Minneapolis, Pittsburgh, Raleigh, NC and St. Louis. CRC fellow Janet Harrah, who serves as the senior director of Northern Kentucky University's Center for Economic Analysis and Development, suggests that it may be time to examine similarly sized cities that are managing to beat the national averages when it comes to personal income. Those include Oklahoma City, Virginia Beach, Baltimore and Washington, D.C.Do Good:• Educate yourself. Read about 2010 Census data for our region and see what you could do to make a difference.• Subscribe to CRC's newsletter so you will get the latest news and updates from the researchers.• Check more data. You can download the 64-page report online.By Elissa YanceyPhoto by Scott Beseler

Medpace moving toward physical, financial growth this summer

Cincinnati-based clinical research organization Medpace is having a year of notable changes, thanks to the continuation of a long-laid plan, and a recently announced partial acquisition.In 2010, Medpace began the relocation of its operations to a new facility on Red Bank and Madison roads in Madisonville. The move, supported in part by a 15-year, 75 percent LEED tax abatement on the first of three planned buildings, a 132,000 square-foot office building.The company has planned from the beginning to construct two additional buildings to house research labs. Construction manager Al Neyer, Inc. recently closed the bidding process for subcontractors for the new buildings, and on May 25 Cincinnati City Council approved a pair of 15-year tax exemptions for the new buildings, which are planned to be built to LEED certified standards. "Originally, when we built the headquarters, we had two labs in Norwood," said company spokesperson Mary Kuramoto. "The plan has always been to move them to the new location."But Medpace's latest news has little to do with its brick-and-mortar developments: the company announced May 23 that affiliates of the global private equity firm CCMP Capital Advisors, LLC, are in talks with the company to acquire an 80-percent ownership share. The acquisitions will allow Medpace to expand its global reach and enhance its ability to conduct phase I-IV clinical studies, said Medpace CEO August Troendle in a press release announcing the move.A spokesperson for CCMP Capital Advisors' New York City office declined to comment on the deal, but noted - as did Medpace via press release - that more news on the deal may be released in June.Writer: Matt CunninghamPhotography by Matt Cunningham

Couple puts life on the line to find expert care at Ronald McDonald House

Angeline is still weeks away from being born, but she is already a miracle for her mother, LaDonna Thompson, and her father, Jared Litke. The young couple from Biloxi learned in April that their daughter-to-be had spina bifida - her spinal cord was literally growing outside of her back. They researched, consulted with experts and weighed heavy options.They could wait until her birth, then face a dangerous operation and growing odds that she might need to have a shunt inserted into her brain or spine to help drain spinal fluid. Or, they could try a risky but promising procedure available at only a handful of hospitals in the country. Fetal surgery to enclose their baby daughter's spinal cord before her birth offered the best chance that she might live a more normal life. "Only four hospitals in the country do it," says Litke, 24. "Vanderbilt and Cincinnati Children's are the top two."So Litke and Thompson, 19, who met while working at Petsmart in Mississippi, made plans to travel north. "We lost our jobs, we lost our home coming up here," Litke says. Though engaged, they don't qualify for the Family Medical Leave Act. They relied on family and friends to do what they could to help.They had three weeks to clear out their belongings and head north. It was a daunting task, but Litke and Thompson didn't hesitate. "Kids always come first," Litke says.Their stay at the Ronald McDonald House in Avondale started this spring. Thompson underwent a three-hour surgery in May to close Angeline's spine. Results looks promising so far, but because of the risks, the parents-to-be will stay in Cincinnati until Angeline's birth in September. The couple settled on the name Angeline early on, Litke explains. The word for "angel" has strong Irish and Italian roots, as do the parents.The Ronald McDonald House never withholds treatment because families can't afford it, but Thompson and Litke wanted to contribute something to offset the cost of treatment. In 2010, the facility housed more than 1,200 families from 49 states and 28 countries. Providing a room costs the agency $90 per day, but the suggested donation amount for families is just $25. Thompson and Litke could scarcely afford any additional expenses, so they decided to start a non-profit, Angeline's Hope, to raise funds for other families in similar conditions. They started collecting pull tabs from canned drinks, mostly via Facebook and friends in Mississippi, to donate to the Ronald McDonald House as well as to raise awareness of the organization's never-ending needs.Just 13 percent of its annual budget actually comes from McDonald's, explains ?Colleen Weinkam, communications manager of the Ronald McDonald House Charities of Greater Cincinnati. Cincinnati Children's Hospital Medical Center contributes 1 percent of the annual budget. But the lion's share of the funding, 84 percent, comes from donations and contributions. Last year, the organization raised more than $16,000 by cashing in hundreds of thousands of pull-tabs. Though it takes more than 300,000 pull-tabs to support a single night's stay in the house, Litke and Thompson were inspired by the House's existing pull-tab donation program. Plus, they wanted to give something back to show their appreciation and support of the people who became their family away from home. So far, they have collected more than 100,000 pull tabs. Their goal is to hit 400,000 before Angeline's birth. "It really does feel great knowing there is that there is all that support there," says Litke. "It's important to know that we are giving our little girl a better shot at living more of a normal life." Do Good:• Become a friend. Get the latest news on Angeline and fundraising on Facebook.• Sponsor a family. Pay for as little as one night for $25 or three months for $2,325 to cover costs for a family that is fighting for its life.• Be a Hero. Pick from more than a dozen options that package donations into categories including a "Basic Baker's" pack, a "Comfort" pack and a "Kitchen" pack.By Elissa YanceyPhoto courtesy Ronald McDonald House Charities of Greater Cincinnati

Read more about Ohio innovation in hiVelocity

hiVelocity tells the story of the new economy in Ohio. It's a narrative of creative people and businesses and what they are doing to create jobs for today and tomorrow. It's the story of a state on the move.Every other Thursday, hiVelocity will present original stories, video and photography to tell that story, from Cleveland to Cincinnati, Marietta to Maumee and parts in between.Read more about Ohio innovation in hiVelocity.

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