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Avondale : Innovation + Startup News

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TEDx hosted by Xavier University for second year

TEDx, an independently organized intellectual conference licensed by the global TED event, will be hosted by Xavier University at the Cintas Center on April 17. Last year's premiere of TedxXavierUniversity was met with great success, and this year's event will include a multitude of speakers.

TEDx was started to mimic the larger TED’s format with multiple speakers, demonstrators and performers who seek to share “ideas worth spreading.” Nicholas Turon took on the lead role in organizing this year’s event with Xavier students who study the full spectrum of academic disciplines.

“I love TED and everything it stands for,” says Turon, who studies music education. “This is something we can be proud of. We’ve helped create an environment you don’t normally get in classes.”

Organized entirely by Xavier students, they view TEDx as an important legacy to leave for future students.

“There’s only so much you can do to change a university in four years,” says Sam Seigle, who is the head of speakers and sponsors for the event. “This is our special opportunity to make a lasting tradition. We hope it will grow more prestigious every year.”

Due to budgeting constraints, the event will have a smaller capacity than last year's. While 2012 reached its registration limit of 400 attendees within a week, this year, there will only be 200 available seats. Turon says the scaled-down event will offer participants a more intimate experience with speakers.

The organizers are eager to make TEDxXavierUniversity a continual success, which relies on spreading the word to promoters and interested audiences. Registration for tickets to the event is available here.

By Sean Peters

Intern in Ohio program launches today, connects students with internships

Today, Detroit-based Digerati launches its Intern in Ohio program to the public, which is sponsored by the University of Toledo. Like eHarmony, the program uses an advanced matching algorithm to match students with internship opportunities.
 
Intern in Ohio is free to both students who are looking for internships and businesses who want to post internships. To register, students and employers visit Intern in Ohio’s website to sign up and create a profile or post internship opportunities. Students fill out a short questionnaire about their preferences, and employers share information about the position. The system then identifies the top seven matches for each student, as well as for each position. When the match is made, both the student and employer are notified, and they must show interest before any contact information is shared.
 
“We encourage diverse companies—large and small, for-profit and nonprofit, government and corporate,” says Wendy Pittman, director of Digerati’s Classroom to Career. “It’s a great chance for employers to broadcast their company and internship program across the state and reach a larger pool of applicants.”
 
Only companies in Ohio can post opportunities to the Intern in Ohio website, but all types of internships are welcome. There are posts for marketing, engineering and social media, among others, says Pittman.
 
The program is open to all students who live in Ohio, whether they’re in-state or out-of-state students. Research shows that not only do internships often lead employment offers after graduation, but that students are more likely to remain in an area where they held and internship.
 
“This is the first replication of the Classroom to Career technology from Michigan to Ohio,” says Pittman. “Experiential learning is a game-changer; and we’re looking forward to working with smaller communities to make a difference.”
 
In 2011, Digerati launched its Intern in Michigan program, which has resulted in more than 127,000 matches and introductions between students and employers. Over 1,000 Michigan businesses have posted 4,824 internship opportunities, and 1,049 colleges and universities in the state use the site.
 
Full disclosure: Soapbox’s parent company, IMG, supplies content to Intern in Ohio on a contractual basis.
 
By Caitlin Koenig
Follow Caitlin on Twitter

Thinking outside the box: Home bakery turns Gail Yisreal into cake boss

Going on maternity leave changed Gail Yisreal’s life in more ways than having a new baby to take care of.
 
When she returned to work, Yisreal says she learned her position was no longer there, so she began to look for a different job.

As wife and mother to a blended family of nine children, she might bake up to 11 birthday cakes in a year. But she hadn’t considered turning her knack for kneading dough into earning dough until she baked a wedding cake for a couple from her family’s place of worship. Not only did they like the cake, they suggested she start selling them.
 
Listening to her fans, Yisreal founded A “Mother’s Touch” Cakes with the nurturing tagline, “Making fresh homemade cakes when you don’t have the time.” Celebrating her two-year anniversary as a registered business in August 2012, A “Mother’s Touch” features signature and custom made flavors of fresh, savory gourmet, organic and vegan cakes and cupcakes that are good—and good for you.
 
“I didn’t know anything about decorating, so I took a class to learn more decorating skills," Yisreal says. "And I was shocked to find out that 95 percent of the cakes you buy are box cakes—because everybody wants the decoration. I started doing some research about the trans-fats and artificial ingredients, and I vowed that everything I baked would always be natural and from scratch.”  
 
After working as a waitress for two years and in management at Starbucks for six years, Yisreal developed a love for coffee. She jokes that most ex-Starbucks managers feel they know enough about coffee to create their own line, which she actually did for A “Mother’s Touch.”
 
Having tried organic coffees with weak flavor profiles, she researched and found Dean’s Beans, a fair-trade pioneer that allowed her to design her own custom blends. Her signature A “Mother’s Touch” blend is made with Mexican and Indonesian beans and pairs with her carrot cake as an after-dinner coffee.
 
“I’m really proud of my coffee and the fact that it really was custom blended for what I wanted to complement my desserts,” Yisreal says. And, true to her mission to serve natural, sustainable goods, she says that her blends are 100 percent organic, fair-trade certified and are shade grown.
 
Being on the scene without a storefront hasn’t stopped Yisreal. Instead, she’s building her brand as the “cupcake lady” who networks everywhere and invites people to taste samples of her creations. Yisreal also tapped into hidden markets by hosting deals through social media.
 
“I did a Living Social promotion last year, which was huge,” Yisreal says. “That first day, I think I got 1,500 hits on my website, and probably about 85 deals, which I thought was really good for people who didn’t know who I was.”
 
And even though she sells more cakes today, the ease of transporting cupcakes built her clientele.
 
“When I first came out, because of my financial situation, literally, cupcakes were paying my rent,” she says. After she and her husband separated, she remembers what it was like to go from making an annual salary of $60,000 to less than $20,000 a year. But she doesn’t do it all alone.
 
“I have three almost-teenage girls; 12, soon to be 15 and 17, so they are my preppers,” Yisreal explains. “It’s hilarious because we’ll be in the kitchen and everybody has their big bonnets on, and they’re scraping carrots, mashing fruit, lining the liners. I have a girlfriend who I’ll sometimes sub-contract out to do deliveries. And if it’s a huge event—like for the Autism Foundation, I had to knock out 40 dozen cupcakes—I have two sisters, and at the time I had just split up with my husband so we were in literally an 800-square-foot apartment. The kitchen was all of maybe 150-square-feet, we put out six-foot tables and we were like an assembly line! It was hilarious, but we got it done. It was like an I Love Lucy episode!”
 
By Mildred Fallen

BIOSTART moves toward service-based model

Fifteen years after opening its doors, BIOSTART, Cincinnati's life sciences start-up center, is changing the way it does business. In order to remain competitive in a fast-changing business market, it is closing its lab space and moving from its location near the University of Cincinnati.

BIOSTART President Carol Frankenstein says the organization will focus exclusively on business services, making the hard shift as its closes its current facility at the Hoxworth Blood Center in September. She says the change was both a business and a strategic decision.

"Today, companies, even at the very early stages, are outsourcing their commercialization and development activity. That includes clinical and preclinical work, development and manufacturing," Frankenstein says. "That increase in outsourcing reduces the cost of getting a product to market. That makes lab space less necessary. Because of the economy, there is so much low-cost and even free space available; our companies have the ability to benefit from that."

BIOSTART serves life sciences entrepreneurs in health care service and product development. Since 1996, it's helped 125 companies launch their business and raise $180 million. Three-fourths of those businesses have had successful exits or are currently in business, the organization reports.

BIOSTART is working with local business advocates, including the Hamilton County Business Center, Uptown Consortium and CincinnatiUSA Regional Chamber to help its 18 tenant companies (which occupy about 65 percent of its space) to relocate.

Frankenstein said BIOSTART is looking for a new space downtown. She will remain with the organization as will three entrepreneurs in residence. The organization has received $500,000 in funding, half from the Ohio Department of Development and half from private sources, to aid in the transition.

"We're using the grant for the next 12 months to explore new service delivery models," she says.

BIOSTART's current business services include helping companies put together a management team and connecting with and applying for funding sources.

By Feoshia Henderson

You can follow Feoshia on Twitter @feoshiawrites


Airway Therapeutics helps premature infants with healthy lung development

In 2008, more than 530,000 babies were born prematurely in the U.S. That's about one in eight babies, according to the March of Dimes. Many have lungs that are not yet fully developed. That's where Airway Therapeutics comes in - the local business was created to help premature infants with their lung development and even survival rates.

Based on ten years of research at Cincinnati Children's Hospital Medical Center, Airway Therapeutics was created to develop a surfactant protein that lines the surface and airways of babies' lungs to help inflate them and keep their air sacs from collapsing.

Airway's initial focus will be on the prevention of bronchopulmonary dysplasia (BPD) and also the prevention and treatment of neonatal respiratory distress syndrome (nRDS) in very premature infants. Normally, lungs mature to produce surfactant in the seventh month of gestation. Very premature infants (before 32 weeks gestation) have generally not developed lung surfactant to make the transition during birth from fluid-filled lungs to lungs that can easily expand to handle air movement. Administering surfactant to these very premature infants shortly after birth allows them to breathe.

Airway's product, rhSP-D, would be added to existing surfactant prior to treating a premature newborn, and has been shown in the lab of Dr. Jeffrey Whitsett to be useful in reducing lung inflammation, a condition associated with BPD.  Dr. Whitsett is chief of the Section of Neonatology, and Perinatal and Pulmonary Biology at Children's. Bringing his research into the market is CEO Steve Linberg, Ph.D., who has more than 30 years of clinical research, drug development and biologic development experience.

The company recently received a seed-stage investment by CincyTech - a Cincinnati-based venture development firm that invests in technology-based startup companies - and the Cincinnati Children's Tomorrow Fund. Each has invested $250,000 as part of a projected $1.2 million seed-stage funding round led by CincyTech.   The company is headquartered at BioStart, the Cincinnati bioscience startup center located in Clifton, which is a previous investor in Airway.

The new investment will allow Airway to meet with the Food and Drug Administration within a few months to confirm their plans to begin developing rhSP-D in combination with an already-available surfactant, and then file an Investigational New Drug (IND) application within 15 months. Linberg estimates a total estimated cost of $25 million to bring the drug to market.

"This drug will save babies that don't survive today and radically improve the lives of millions of others," says CincyTech Executive-in-Residence Mike Venerable.

Writer: Sarah Blazak
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